Human Activin A


Catalog Number: 100-43

Human Activin A
Alternative Names: Inhibin beta-1, FRP, FSH-releasing protein

Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMADproteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Human Activin A has 100% amino acid sequence identity to mouse, rat, porcine, bovine and feline proteins. Recombinant human Activin A is a non-glycosylated homodimer, containing two 117 amino acid chains, with a total molecular weight of 26.2 kDa.

Data Sheet (PDF)

 

 

 

 

 

 

 

 


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